One of the reasons Tramadol is frequently prescribed is its dual mechanism of action. It binds to the mu-opioid receptors in the brain, which helps block pain signals. In addition to its opioid activity, it also inhibits the reuptake of serotonin and norepinephrine, two neurotransmitters that play a key role in how the body processes pain and mood. This dual effect not only provides pain relief but can also improve mood, which is particularly useful for individuals whose pain is associated with depression or anxiety. However, this mechanism also increases the risk of certain side effects, particularly when Tramadol is taken with other medications that affect serotonin levels.