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Tapered columns are structural elements whose cross-sectional dimensions gradually decrease from the base towards the top. Unlike uniform columns, tapered columns optimize material use, enhance architectural aesthetics, and improve load distribution. The subtle reduction in size helps to minimize dead loads and increase stability, offering both functional strength and visual appeal in construction. Typically crafted from steel, concrete, or composite materials, tapered columns are precisely engineered to match specific load-bearing requirements. Their design improves structural efficiency by directing loads smoothly to the foundation, thereby reducing bending moments and enhancing overall building resilience.

Polynucleotides can undergo modifications that affect their function; for example, methylation can regulate gene expression without altering the DNA sequence itself.

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